Have these materials been tested on the SLS?

From: #PHUA KHIANG SONG KENNETH# (P7207064Z@ntu.edu.sg)
Date: Mon Dec 01 1997 - 04:54:50 EET


> I have been doing some literature search for materials which are
> suitable for fabricating implantable drug delivery devices for my
> research project. Here are some of them which I found to be quite
> appropriate. Could anyone help me verify if they can be/have ever been
> used on the SLS? The materials are:
>
> 1. Polyethyleneglycol (abbrev. PEG) 400 (melting temperature range:
> 4 degrees celcius to 8 degrees celcius)
>
> 2. PEG 600 (melting temp. range: 20 deg. cel. to 25 deg. cel.)
>
> 3. PEG 1500 (melting temp. range: 44 deg. cel. to 48 deg. cel.)
>
> 4. Stearic Acid (melting temp.: 70 deg. cel.)
>
> From past knowledge, most implantable erodible devices are composed
> of:
>
> 1. Polyester and
> 2. Polyamides
>
> The polyester comes from the polylactide or polyglycolide family and
> have been FDA approved. They are well-tested with a long and
> favourable clinical record.
>
> Have these been tried and tested on SLS, too? Or are they feasible to
> be used at all?
>
Regards,

> Kenneth
Graduate Student
Biomedical Engineering Research Centre
Nanyang Technological University
>
>



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